BDBM50121026 2-[3,4-Dihydroxy-5-(3-methyl-but-2-enyl)-phenyl]-8-(1,1-dimethyl-allyl)-3,5,7-trihydroxy-chromen-4-one::CHEMBL323712

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-c1cc(cc(-[#8])c1-[#8])-c1oc2c(c(-[#8])cc(-[#8])c2c(=O)c1-[#8])C([#6])([#6])[#6]=[#6]

InChI Key: InChIKey=XCKYBRFHABGHMT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50121026   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-glucosidase MAL62 (Saccharomyces cerevisiae)	BDBM50121026 (2-[3,4-Dihydroxy-5-(3-methyl-but-2-enyl)-phenyl]-8...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1cc(cc(-[#8])c1-[#8])-c1oc2c(c(-[#8])cc(-[#8])c2c(=O)c1-[#8])C([#6])([#6])[#6]=[#6] Show InChI InChI=1S/C25H26O7/c1-6-25(4,5)19-16(27)11-15(26)18-21(30)22(31)23(32-24(18)19)14-9-13(8-7-12(2)3)20(29)17(28)10-14/h6-7,9-11,26-29,31H,1,8H2,2-5H3	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.60E+9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of baker's yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate by spectrophotometry				Citation and Details Article DOI: 10.1007/s00044-011-9938-0 BindingDB Entry DOI: 10.7270/Q29W0JBG
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50121026 (2-[3,4-Dihydroxy-5-(3-methyl-but-2-enyl)-phenyl]-8...) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1cc(cc(-[#8])c1-[#8])-c1oc2c(c(-[#8])cc(-[#8])c2c(=O)c1-[#8])C([#6])([#6])[#6]=[#6] Show InChI InChI=1S/C25H26O7/c1-6-25(4,5)19-16(27)11-15(26)18-21(30)22(31)23(32-24(18)19)14-9-13(8-7-12(2)3)20(29)17(28)10-14/h6-7,9-11,26-29,31H,1,8H2,2-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description The inhibitory activity of the compound tested against human Protein-tyrosine phosphatase 1B enzyme				Bioorg Med Chem Lett 12: 3387-90 (2002) BindingDB Entry DOI: 10.7270/Q2HH6JF5
					More data for this Ligand-Target Pair