null

SMILES: COc1cccc(c1)C(=O)NCCCCN1CCN(CC1)c1nccc2ccccc12

InChI Key: InChIKey=MGZOXAOAEVISHM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50122053   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50122053 (CHEMBL152587 | N-[4-(4-Isoquinolin-1-yl-piperazin-...) Show SMILES COc1cccc(c1)C(=O)NCCCCN1CCN(CC1)c1nccc2ccccc12 Show InChI InChI=1S/C25H30N4O2/c1-31-22-9-6-8-21(19-22)25(30)27-12-4-5-14-28-15-17-29(18-16-28)24-23-10-3-2-7-20(23)11-13-26-24/h2-3,6-11,13,19H,4-5,12,14-18H2,1H3,(H,27,30)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	9.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Curated by ChEMBL					Assay Description Binding affinity towards Dopamine receptor D3 of rat using [3H]spiroperidol as radioligand				J Med Chem 45: 5727-35 (2002) BindingDB Entry DOI: 10.7270/Q2TT4RQC
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50122053 (CHEMBL152587 | N-[4-(4-Isoquinolin-1-yl-piperazin-...) Show SMILES COc1cccc(c1)C(=O)NCCCCN1CCN(CC1)c1nccc2ccccc12 Show InChI InChI=1S/C25H30N4O2/c1-31-22-9-6-8-21(19-22)25(30)27-12-4-5-14-28-15-17-29(18-16-28)24-23-10-3-2-7-20(23)11-13-26-24/h2-3,6-11,13,19H,4-5,12,14-18H2,1H3,(H,27,30)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	12.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor from rat hippocampal membranes				J Med Chem 45: 5727-35 (2002) BindingDB Entry DOI: 10.7270/Q2TT4RQC
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50122053 (CHEMBL152587 | N-[4-(4-Isoquinolin-1-yl-piperazin-...) Show SMILES COc1cccc(c1)C(=O)NCCCCN1CCN(CC1)c1nccc2ccccc12 Show InChI InChI=1S/C25H30N4O2/c1-31-22-9-6-8-21(19-22)25(30)27-12-4-5-14-28-15-17-29(18-16-28)24-23-10-3-2-7-20(23)11-13-26-24/h2-3,6-11,13,19H,4-5,12,14-18H2,1H3,(H,27,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	168	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Curated by ChEMBL					Assay Description Binding affinity towards human Dopamine receptor D4 using [3H]spiroperidol as radioligand				J Med Chem 45: 5727-35 (2002) BindingDB Entry DOI: 10.7270/Q2TT4RQC
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50122053 (CHEMBL152587 | N-[4-(4-Isoquinolin-1-yl-piperazin-...) Show SMILES COc1cccc(c1)C(=O)NCCCCN1CCN(CC1)c1nccc2ccccc12 Show InChI InChI=1S/C25H30N4O2/c1-31-22-9-6-8-21(19-22)25(30)27-12-4-5-14-28-15-17-29(18-16-28)24-23-10-3-2-7-20(23)11-13-26-24/h2-3,6-11,13,19H,4-5,12,14-18H2,1H3,(H,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Bari Curated by ChEMBL					Assay Description Binding affinity towards human Dopamine receptor D2 using [3H]spiroperidol as radioligand				J Med Chem 45: 5727-35 (2002) BindingDB Entry DOI: 10.7270/Q2TT4RQC
					More data for this Ligand-Target Pair