BDBM50122607 3-(Benzylamino-methyl)-4,6-dichloro-1H-indole-2-carboxylic acid::CHEMBL163465

SMILES: OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1CNCc1ccccc1

InChI Key: InChIKey=PXPIPISKMPWOST-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50122607   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50122607 (3-(Benzylamino-methyl)-4,6-dichloro-1H-indole-2-ca...) Show SMILES OC(=O)c1[nH]c2cc(Cl)cc(Cl)c2c1CNCc1ccccc1 Show InChI InChI=1S/C17H14Cl2N2O2/c18-11-6-13(19)15-12(16(17(22)23)21-14(15)7-11)9-20-8-10-4-2-1-3-5-10/h1-7,20-21H,8-9H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johannes Gutenberg-Universität Curated by ChEMBL					Assay Description Tested for the affinity for the glycine binding site of the N-methyl-D-aspartate glutamate receptor using pig brain membranes in binding assay with [...				J Med Chem 46: 64-73 (2002) Article DOI: 10.1021/jm020955n BindingDB Entry DOI: 10.7270/Q2NZ8703
					More data for this Ligand-Target Pair