BDBM50123316 2-(3-Bromo-4-methyl-phenyl)-7-methoxy-6-oxazol-5-yl-1H-quinolin-4-one::CHEMBL356371

SMILES: COc1cc2nc(cc(O)c2cc1-c1cnco1)-c1ccc(C)c(Br)c1

InChI Key: InChIKey=GLXOVZZBXQWVJI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123316   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50123316 (2-(3-Bromo-4-methyl-phenyl)-7-methoxy-6-oxazol-5-y...) Show SMILES COc1cc2nc(cc(O)c2cc1-c1cnco1)-c1ccc(C)c(Br)c1 Show InChI InChI=1S/C20H15BrN2O3/c1-11-3-4-12(5-15(11)21)16-7-18(24)13-6-14(20-9-22-10-26-20)19(25-2)8-17(13)23-16/h3-10H,1-2H3,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb PRI Curated by ChEMBL					Assay Description Inhibition of human inosine monophosphate dehydrogenase IMPDH II				Bioorg Med Chem Lett 13: 543-6 (2003) BindingDB Entry DOI: 10.7270/Q2SJ1JZT
					More data for this Ligand-Target Pair