null

SMILES: Nc1ccccc1NC(=O)\C=C\c1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)nc1

InChI Key: InChIKey=NXBKVLUVOQBPCG-GZTJUZNOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50123968   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50123968 (CHEMBL166883 | N-(2-Amino-phenyl)-3-[6-(biphenyl-4...) Show SMILES Nc1ccccc1NC(=O)\C=C\c1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)nc1 Show InChI InChI=1S/C26H22N4O3S/c27-23-8-4-5-9-24(23)29-26(31)17-11-19-10-16-25(28-18-19)30-34(32,33)22-14-12-21(13-15-22)20-6-2-1-3-7-20/h1-18H,27H2,(H,28,30)(H,29,31)/b17-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
MethylGene Inc. Curated by ChEMBL					Assay Description Inhibitory activity on partially purified recombinant human Histone deacetylase 1 (HDAC-1)				J Med Chem 46: 820-30 (2003) Article DOI: 10.1021/jm020377a BindingDB Entry DOI: 10.7270/Q22V2FG8
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50123968 (CHEMBL166883 | N-(2-Amino-phenyl)-3-[6-(biphenyl-4...) Show SMILES Nc1ccccc1NC(=O)\C=C\c1ccc(NS(=O)(=O)c2ccc(cc2)-c2ccccc2)nc1 Show InChI InChI=1S/C26H22N4O3S/c27-23-8-4-5-9-24(23)29-26(31)17-11-19-10-16-25(28-18-19)30-34(32,33)22-14-12-21(13-15-22)20-6-2-1-3-7-20/h1-18H,27H2,(H,28,30)(H,29,31)/b17-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	US Patent	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	37
Methylgene Inc. US Patent					Assay Description For deacetylase assays, 20,000 cpm of the [3H]-metabolically labeled acetylated histone substrate (M. Yoshida et al., J. Biol. Chem. 265(28): 17174-1...				US Patent US8796330 (2014) BindingDB Entry DOI: 10.7270/Q22B8WQW
					More data for this Ligand-Target Pair