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SMILES: Nc1ccccc1NC(=O)\C=C\c1ccc(NS(=O)(=O)c2cccc3oc4ccccc4c23)cc1

InChI Key: InChIKey=WUJNLYVRMLHWLP-SAPNQHFASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123971   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 1


(Homo sapiens (Human))		BDBM50123971
PNG
(CHEMBL168221 | N-(2-Amino-phenyl)-3-[4-(dibenzofur...)
Show SMILES Nc1ccccc1NC(=O)\C=C\c1ccc(NS(=O)(=O)c2cccc3oc4ccccc4c23)cc1
Show InChI InChI=1S/C27H21N3O4S/c28-21-7-2-3-8-22(21)29-26(31)17-14-18-12-15-19(16-13-18)30-35(32,33)25-11-5-10-24-27(25)20-6-1-4-9-23(20)34-24/h1-17,30H,28H2,(H,29,31)/b17-14+
PDB
MMDB

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Similars
Article
PubMed
n/an/a 400n/an/an/an/an/an/a



MethylGene Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity on partially purified recombinant human Histone deacetylase 1 (HDAC-1)

J Med Chem 46: 820-30 (2003)


Article DOI: 10.1021/jm020377a
BindingDB Entry DOI: 10.7270/Q22V2FG8
More data for this
Ligand-Target Pair