BDBM50124171 4-methoxyphenylsulfamide::CHEMBL165878::N-(4-methoxyphenyl)sulfamide

SMILES: COc1ccc(NS(N)(=O)=O)cc1

InChI Key: InChIKey=ICWBFSCBEZAOCT-UHFFFAOYSA-N

Data: 4 KI  2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50124171   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50124171 (4-methoxyphenylsulfamide | CHEMBL165878 | N-(4-met...) Show SMILES COc1ccc(NS(N)(=O)=O)cc1 Show InChI InChI=1S/C7H10N2O3S/c1-12-7-4-2-6(3-5-7)9-13(8,10)11/h2-5,9H,1H3,(H2,8,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against human cloned isoenzyme carbonic anhydrase II (hCA II), by esterase method.				Bioorg Med Chem Lett 13: 837-40 (2003) BindingDB Entry DOI: 10.7270/Q2GB24MW
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50124171 (4-methoxyphenylsulfamide | CHEMBL165878 | N-(4-met...) Show SMILES COc1ccc(NS(N)(=O)=O)cc1 Show InChI InChI=1S/C7H10N2O3S/c1-12-7-4-2-6(3-5-7)9-13(8,10)11/h2-5,9H,1H3,(H2,8,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against human cloned isoenzyme carbonic anhydrase I (hCA I), by esterase method.				Bioorg Med Chem Lett 13: 837-40 (2003) BindingDB Entry DOI: 10.7270/Q2GB24MW
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50124171 (4-methoxyphenylsulfamide | CHEMBL165878 | N-(4-met...) Show SMILES COc1ccc(NS(N)(=O)=O)cc1 Show InChI InChI=1S/C7H10N2O3S/c1-12-7-4-2-6(3-5-7)9-13(8,10)11/h2-5,9H,1H3,(H2,8,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human CA2 by carbon dioxide hydration				J Med Chem 49: 3496-500 (2006) Article DOI: 10.1021/jm058279n BindingDB Entry DOI: 10.7270/Q2XP75RG
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50124171 (4-methoxyphenylsulfamide | CHEMBL165878 | N-(4-met...) Show SMILES COc1ccc(NS(N)(=O)=O)cc1 Show InChI InChI=1S/C7H10N2O3S/c1-12-7-4-2-6(3-5-7)9-13(8,10)11/h2-5,9H,1H3,(H2,8,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.88E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Inhibition of human CA2 by 4-nitrophenyl acetate hydrolysis				J Med Chem 49: 3496-500 (2006) Article DOI: 10.1021/jm058279n BindingDB Entry DOI: 10.7270/Q2XP75RG
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50124171 (4-methoxyphenylsulfamide | CHEMBL165878 | N-(4-met...) Show SMILES COc1ccc(NS(N)(=O)=O)cc1 Show InChI InChI=1S/C7H10N2O3S/c1-12-7-4-2-6(3-5-7)9-13(8,10)11/h2-5,9H,1H3,(H2,8,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	2.65E+3	n/a	n/a	n/a	7.5	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Binding affinity to human CA2 in presence of sodium sulfate and ANS at pH 7.5 by ThermoFluor assay				J Med Chem 49: 3496-500 (2006) Article DOI: 10.1021/jm058279n BindingDB Entry DOI: 10.7270/Q2XP75RG
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50124171 (4-methoxyphenylsulfamide | CHEMBL165878 | N-(4-met...) Show SMILES COc1ccc(NS(N)(=O)=O)cc1 Show InChI InChI=1S/C7H10N2O3S/c1-12-7-4-2-6(3-5-7)9-13(8,10)11/h2-5,9H,1H3,(H2,8,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	7.4	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Binding affinity to human CA2 at pH 7.4 by ThermoFluor assay				J Med Chem 49: 3496-500 (2006) Article DOI: 10.1021/jm058279n BindingDB Entry DOI: 10.7270/Q2XP75RG
					More data for this Ligand-Target Pair