BDBM50124534 2-Methyl-1,2-dihydro-quinazolin-4-ylamine::2-methyl-1,2-dihydroquinazolin-4-amine::CHEMBL355856

SMILES: CC1Nc2ccccc2C(N)=N1

InChI Key: InChIKey=BFASSLCZFJPKRD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50124534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50124534 (2-Methyl-1,2-dihydro-quinazolin-4-ylamine | 2-meth...) Show SMILES CC1Nc2ccccc2C(N)=N1 |c:11| Show InChI InChI=1S/C9H11N3/c1-6-11-8-5-3-2-4-7(8)9(10)12-6/h2-6,11H,1H3,(H2,10,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of iNOS				J Med Chem 51: 2481-91 (2008) Article DOI: 10.1021/jm701314u BindingDB Entry DOI: 10.7270/Q2GX4CF5
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50124534 (2-Methyl-1,2-dihydro-quinazolin-4-ylamine | 2-meth...) Show SMILES CC1Nc2ccccc2C(N)=N1 |c:11| Show InChI InChI=1S/C9H11N3/c1-6-11-8-5-3-2-4-7(8)9(10)12-6/h2-6,11H,1H3,(H2,10,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca R& D Charnwood Curated by ChEMBL					Assay Description Inhibitory activity of compound against human inducible nitiric oxide synthase				J Med Chem 46: 913-6 (2003) Article DOI: 10.1021/jm0255926 BindingDB Entry DOI: 10.7270/Q2S75H3M
					More data for this Ligand-Target Pair