BindingDB logo
myBDB logout

null

SMILES: [O-][N+](=O)c1cc(Cl)ccc1-c1ccc(o1)C(=O)N1CCc2c([nH]c3ccccc23)[C@@H]1c1ccc2OCOc2c1

InChI Key: InChIKey=BFFZFBPUOMXAPD-NDEPHWFRSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125125   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))		BDBM50125125
PNG
(((S)-1-Benzo[1,3]dioxol-5-yl-1,3,4,9-tetrahydro-be...)
Show SMILES [O-][N+](=O)c1cc(Cl)ccc1-c1ccc(o1)C(=O)N1CCc2c([nH]c3ccccc23)[C@@H]1c1ccc2OCOc2c1
Show InChI InChI=1S/C29H20ClN3O6/c30-17-6-7-20(22(14-17)33(35)36)23-9-10-25(39-23)29(34)32-12-11-19-18-3-1-2-4-21(18)31-27(19)28(32)16-5-8-24-26(13-16)38-15-37-24/h1-10,13-14,28,31H,11-12,15H2/t28-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development L.L.C.

Curated by ChEMBL


Assay Description
Inhibition of PDE5 (Phosphodiesterase) from human corpus cavernosum

Bioorg Med Chem Lett 13: 761-5 (2003)


BindingDB Entry DOI: 10.7270/Q29886CM
More data for this
Ligand-Target Pair