BDBM50125244 3-(3-Amino-4-chloro-phenyl)-5-methyl-4,5-dihydro-isoxazole-5-carboxylic acid (2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL7905

SMILES: CC1(CC(=NO1)c1ccc(Cl)c(N)c1)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O

InChI Key: InChIKey=YBRYARGLQPBMTO-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125244   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50125244 (3-(3-Amino-4-chloro-phenyl)-5-methyl-4,5-dihydro-i...) Show SMILES CC1(CC(=NO1)c1ccc(Cl)c(N)c1)C(=O)Nc1ccc(cc1)-c1ccccc1S(N)(=O)=O |c:3| Show InChI InChI=1S/C23H21ClN4O4S/c1-23(13-20(28-32-23)15-8-11-18(24)19(25)12-15)22(29)27-16-9-6-14(7-10-16)17-4-2-3-5-21(17)33(26,30)31/h2-12H,13,25H2,1H3,(H,27,29)(H2,26,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. Curated by ChEMBL					Assay Description Inhibitory activity against factor Xa using human purified enzyme.				Bioorg Med Chem Lett 13: 1023-8 (2003) BindingDB Entry DOI: 10.7270/Q21R6PWQ
					More data for this Ligand-Target Pair