BDBM50125706 3,5-Dichloro-N-{3-[3-(4-trifluoromethyl-phenyl)-ureido]-phenyl}-benzamide::CHEMBL441409

SMILES: FC(F)(F)c1ccc(NC(=O)Nc2cccc(NC(=O)c3cc(Cl)cc(Cl)c3)c2)cc1

InChI Key: InChIKey=OLWMPQAMLNTFCC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclophilin A (Rattus norvegicus)	BDBM50125706 (3,5-Dichloro-N-{3-[3-(4-trifluoromethyl-phenyl)-ur...) Show SMILES FC(F)(F)c1ccc(NC(=O)Nc2cccc(NC(=O)c3cc(Cl)cc(Cl)c3)c2)cc1 Show InChI InChI=1S/C21H14Cl2F3N3O2/c22-14-8-12(9-15(23)10-14)19(30)27-17-2-1-3-18(11-17)29-20(31)28-16-6-4-13(5-7-16)21(24,25)26/h1-11H,(H,27,30)(H2,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of the rotamase activity of cyclophilin A (CyPA)				J Med Chem 46: 1112-5 (2003) Article DOI: 10.1021/jm020409u BindingDB Entry DOI: 10.7270/Q2V1244X
					More data for this Ligand-Target Pair