BDBM50125711 1-(2,4-Dimethyl-phenyl)-3-{3-[3-(2,4-dimethyl-phenyl)-ureido]-phenyl}-urea::CHEMBL13640

SMILES: Cc1ccc(NC(=O)Nc2cccc(NC(=O)Nc3ccc(C)cc3C)c2)c(C)c1

InChI Key: InChIKey=DWBRZVRBQYYJFR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125711   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclophilin A (Rattus norvegicus)	BDBM50125711 (1-(2,4-Dimethyl-phenyl)-3-{3-[3-(2,4-dimethyl-phen...) Show SMILES Cc1ccc(NC(=O)Nc2cccc(NC(=O)Nc3ccc(C)cc3C)c2)c(C)c1 Show InChI InChI=1S/C24H26N4O2/c1-15-8-10-21(17(3)12-15)27-23(29)25-19-6-5-7-20(14-19)26-24(30)28-22-11-9-16(2)13-18(22)4/h5-14H,1-4H3,(H2,25,27,29)(H2,26,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of the rotamase activity of cyclophilin A (CyPA)				J Med Chem 46: 1112-5 (2003) Article DOI: 10.1021/jm020409u BindingDB Entry DOI: 10.7270/Q2V1244X
					More data for this Ligand-Target Pair