BDBM50125715 3,5-Dichloro-N-[3-(3-phenyl-ureido)-phenyl]-benzamide::CHEMBL13423

SMILES: Clc1cc(Cl)cc(c1)C(=O)Nc1cccc(NC(=O)Nc2ccccc2)c1

InChI Key: InChIKey=SVWKENWRMBXWBG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclophilin A (Rattus norvegicus)	BDBM50125715 (3,5-Dichloro-N-[3-(3-phenyl-ureido)-phenyl]-benzam...) Show SMILES Clc1cc(Cl)cc(c1)C(=O)Nc1cccc(NC(=O)Nc2ccccc2)c1 Show InChI InChI=1S/C20H15Cl2N3O2/c21-14-9-13(10-15(22)11-14)19(26)23-17-7-4-8-18(12-17)25-20(27)24-16-5-2-1-3-6-16/h1-12H,(H,23,26)(H2,24,25,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of the rotamase activity of cyclophilin A (CyPA)				J Med Chem 46: 1112-5 (2003) Article DOI: 10.1021/jm020409u BindingDB Entry DOI: 10.7270/Q2V1244X
					More data for this Ligand-Target Pair