BDBM50125729 3,5-Dichloro-N-{3-[3-(2,4-dibromo-phenyl)-ureido]-phenyl}-benzamide::CHEMBL13686

SMILES: Clc1cc(Cl)cc(c1)C(=O)Nc1cccc(NC(=O)Nc2ccc(Br)cc2Br)c1

InChI Key: InChIKey=QQUUZOHRSHGJKE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125729   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclophilin A (Rattus norvegicus)	BDBM50125729 (3,5-Dichloro-N-{3-[3-(2,4-dibromo-phenyl)-ureido]-...) Show SMILES Clc1cc(Cl)cc(c1)C(=O)Nc1cccc(NC(=O)Nc2ccc(Br)cc2Br)c1 Show InChI InChI=1S/C20H13Br2Cl2N3O2/c21-12-4-5-18(17(22)8-12)27-20(29)26-16-3-1-2-15(10-16)25-19(28)11-6-13(23)9-14(24)7-11/h1-10H,(H,25,28)(H2,26,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of the rotamase activity of cyclophilin A (CyPA)				J Med Chem 46: 1112-5 (2003) Article DOI: 10.1021/jm020409u BindingDB Entry DOI: 10.7270/Q2V1244X
					More data for this Ligand-Target Pair