BDBM50125966 CHEMBL3627814

SMILES: O=C1N(CCc2nc3ccccc3c(=O)n2-c2ccc3[nH]ccc3c2)C(=O)c2ccccc12

InChI Key: InChIKey=LSOUCLFRMMRJSW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125966   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50125966 (CHEMBL3627814) Show SMILES O=C1N(CCc2nc3ccccc3c(=O)n2-c2ccc3[nH]ccc3c2)C(=O)c2ccccc12 Show InChI InChI=1S/C26H18N4O3/c31-24-18-5-1-2-6-19(18)25(32)29(24)14-12-23-28-22-8-4-3-7-20(22)26(33)30(23)17-9-10-21-16(15-17)11-13-27-21/h1-11,13,15,27H,12,14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE10A (unknown origin)				Bioorg Med Chem Lett 25: 4893-8 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4M9Z
					More data for this Ligand-Target Pair