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SMILES: CC(=O)N(CCc1nc2ccccc2c(=O)n1-c1ccc(cc1)-c1ccccc1)C(C)=O

InChI Key: InChIKey=SPLOODKBGBMNNP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125986   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))		BDBM50125986
PNG
(CHEMBL3627805)
Show SMILES CC(=O)N(CCc1nc2ccccc2c(=O)n1-c1ccc(cc1)-c1ccccc1)C(C)=O
Show InChI InChI=1S/C26H23N3O3/c1-18(30)28(19(2)31)17-16-25-27-24-11-7-6-10-23(24)26(32)29(25)22-14-12-21(13-15-22)20-8-4-3-5-9-20/h3-15H,16-17H2,1-2H3
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 49n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of PDE10A (unknown origin)

Bioorg Med Chem Lett 25: 4893-8 (2015)


BindingDB Entry DOI: 10.7270/Q2RJ4M9Z
More data for this
Ligand-Target Pair