BDBM50125988 CHEMBL3627807

SMILES: COc1ccc(cc1OC)-n1c(CCN(C(C)=O)C(C)=O)nc2ccccc2c1=O

InChI Key: InChIKey=SLXUNWZZMWQWKL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125988   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50125988 (CHEMBL3627807) Show SMILES COc1ccc(cc1OC)-n1c(CCN(C(C)=O)C(C)=O)nc2ccccc2c1=O Show InChI InChI=1S/C22H23N3O5/c1-14(26)24(15(2)27)12-11-21-23-18-8-6-5-7-17(18)22(28)25(21)16-9-10-19(29-3)20(13-16)30-4/h5-10,13H,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE10A (unknown origin)				Bioorg Med Chem Lett 25: 4893-8 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4M9Z
					More data for this Ligand-Target Pair