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SMILES: COc1ccc(cc1)-n1c(CCN(C(C)=O)C(C)=O)nc2c(Cl)cccc2c1=O

InChI Key: InChIKey=HNGZKBLENRCVOS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125992   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))		BDBM50125992
PNG
(CHEMBL3627811)
Show SMILES COc1ccc(cc1)-n1c(CCN(C(C)=O)C(C)=O)nc2c(Cl)cccc2c1=O
Show InChI InChI=1S/C21H20ClN3O4/c1-13(26)24(14(2)27)12-11-19-23-20-17(5-4-6-18(20)22)21(28)25(19)15-7-9-16(29-3)10-8-15/h4-10H,11-12H2,1-3H3
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MMDB

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PC cid
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PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of PDE10A (unknown origin)

Bioorg Med Chem Lett 25: 4893-8 (2015)


BindingDB Entry DOI: 10.7270/Q2RJ4M9Z
More data for this
Ligand-Target Pair