BDBM50125994 CHEMBL3627813

SMILES: COc1ccc(cc1)-n1c(CCN(C(C)=O)C(C)=O)nc2cc(C)ccc2c1=O

InChI Key: InChIKey=IEJPVEWITHTUGT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125994   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50125994 (CHEMBL3627813) Show SMILES COc1ccc(cc1)-n1c(CCN(C(C)=O)C(C)=O)nc2cc(C)ccc2c1=O Show InChI InChI=1S/C22H23N3O4/c1-14-5-10-19-20(13-14)23-21(11-12-24(15(2)26)16(3)27)25(22(19)28)17-6-8-18(29-4)9-7-17/h5-10,13H,11-12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of PDE10A (unknown origin)				Bioorg Med Chem Lett 25: 4893-8 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4M9Z
					More data for this Ligand-Target Pair