BDBM50126273 (5-Phenyl-oxazol-2-yl)-quinazolin-7-yl-amine::CHEMBL285813

SMILES: N(c1ncc(o1)-c1ccccc1)c1ccc2cncnc2c1

InChI Key: InChIKey=DZZWRXILSUQKPJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50126273 ((5-Phenyl-oxazol-2-yl)-quinazolin-7-yl-amine | CHE...) Show SMILES N(c1ncc(o1)-c1ccccc1)c1ccc2cncnc2c1 Show InChI InChI=1S/C17H12N4O/c1-2-4-12(5-3-1)16-10-19-17(22-16)21-14-7-6-13-9-18-11-20-15(13)8-14/h1-11H,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)				Bioorg Med Chem Lett 13: 1345-8 (2003) BindingDB Entry DOI: 10.7270/Q2CV4H3Q
					More data for this Ligand-Target Pair