BDBM50126283 1-Isoquinolin-6-yl-3-p-tolyl-urea::CHEMBL29927

SMILES: Cc1ccc(NC(=O)Nc2ccc3cnccc3c2)cc1

InChI Key: InChIKey=UZULLQXZQITGOJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50126283   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50126283 (1-Isoquinolin-6-yl-3-p-tolyl-urea | CHEMBL29927) Show SMILES Cc1ccc(NC(=O)Nc2ccc3cnccc3c2)cc1 Show InChI InChI=1S/C17H15N3O/c1-12-2-5-15(6-3-12)19-17(21)20-16-7-4-14-11-18-9-8-13(14)10-16/h2-11H,1H3,(H2,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	247	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibitory activity of the compound against inosine 5'-inosine monophosphate dehydrogenase type II (IMPDH II)				Bioorg Med Chem Lett 13: 1345-8 (2003) BindingDB Entry DOI: 10.7270/Q2CV4H3Q
					More data for this Ligand-Target Pair