BindingDB PrimarySearch

BDBM50126604 4-(N-benzyl-4-methoxyphenylsulfonamido)-8-ethyl-N-hydroxyquinoline-3-carboxamide::4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-ethyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL290948

SMILES: CCc1cccc2c(N(Cc3ccccc3)S(=O)(=O)c3ccc(OC)cc3)c(cnc12)C(=O)NO

InChI Key: InChIKey=OMMFNEZCURCLPN-UHFFFAOYSA-N

Data: 5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50126604
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50126604 (4-(N-benzyl-4-methoxyphenylsulfonamido)-8-ethyl-N-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloproteinase 9 (MMP-9).				Bioorg Med Chem Lett 13: 1487-90 (2003) BindingDB Entry DOI: 10.7270/Q29W0DW0
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50126604 (4-(N-benzyl-4-methoxyphenylsulfonamido)-8-ethyl-N-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloproteinase 13 (MMP-13).				Bioorg Med Chem Lett 13: 1487-90 (2003) BindingDB Entry DOI: 10.7270/Q29W0DW0
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50126604 (4-(N-benzyl-4-methoxyphenylsulfonamido)-8-ethyl-N-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	191	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP1				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
Pomona College Curated by ChEMBL					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50126604 (4-(N-benzyl-4-methoxyphenylsulfonamido)-8-ethyl-N-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	314	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against TACE.				Bioorg Med Chem Lett 13: 1487-90 (2003) BindingDB Entry DOI: 10.7270/Q29W0DW0
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50126604 (4-(N-benzyl-4-methoxyphenylsulfonamido)-8-ethyl-N-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	192	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloproteinase 1 (MMP-1).				Bioorg Med Chem Lett 13: 1487-90 (2003) BindingDB Entry DOI: 10.7270/Q29W0DW0
Wyeth-Ayerst Research Curated by ChEMBL					More data for this Ligand-Target Pair