BDBM50126609 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL429336

SMILES: COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2n(nc(C)c12)-c1ccccc1)C(=O)NO

InChI Key: InChIKey=KWWNNPAPYSJGQH-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50126609   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50126609 (4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2n(nc(C)c12)-c1ccccc1)C(=O)NO Show InChI InChI=1S/C27H24N6O5S/c1-18-24-25(23(27(34)31-35)16-29-26(24)33(30-18)20-8-4-3-5-9-20)32(17-19-7-6-14-28-15-19)39(36,37)22-12-10-21(38-2)11-13-22/h3-16,35H,17H2,1-2H3,(H,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloproteinase 9 (MMP-9).				Bioorg Med Chem Lett 13: 1487-90 (2003) BindingDB Entry DOI: 10.7270/Q29W0DW0
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50126609 (4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2n(nc(C)c12)-c1ccccc1)C(=O)NO Show InChI InChI=1S/C27H24N6O5S/c1-18-24-25(23(27(34)31-35)16-29-26(24)33(30-18)20-8-4-3-5-9-20)32(17-19-7-6-14-28-15-19)39(36,37)22-12-10-21(38-2)11-13-22/h3-16,35H,17H2,1-2H3,(H,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloproteinase 13 (MMP-13).				Bioorg Med Chem Lett 13: 1487-90 (2003) BindingDB Entry DOI: 10.7270/Q29W0DW0
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50126609 (4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2n(nc(C)c12)-c1ccccc1)C(=O)NO Show InChI InChI=1S/C27H24N6O5S/c1-18-24-25(23(27(34)31-35)16-29-26(24)33(30-18)20-8-4-3-5-9-20)32(17-19-7-6-14-28-15-19)39(36,37)22-12-10-21(38-2)11-13-22/h3-16,35H,17H2,1-2H3,(H,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against matrix metalloproteinase 1 (MMP-1).				Bioorg Med Chem Lett 13: 1487-90 (2003) BindingDB Entry DOI: 10.7270/Q29W0DW0
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50126609 (4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2n(nc(C)c12)-c1ccccc1)C(=O)NO Show InChI InChI=1S/C27H24N6O5S/c1-18-24-25(23(27(34)31-35)16-29-26(24)33(30-18)20-8-4-3-5-9-20)32(17-19-7-6-14-28-15-19)39(36,37)22-12-10-21(38-2)11-13-22/h3-16,35H,17H2,1-2H3,(H,31,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory activity against TACE.				Bioorg Med Chem Lett 13: 1487-90 (2003) BindingDB Entry DOI: 10.7270/Q29W0DW0
					More data for this Ligand-Target Pair