BDBM50127596 2-(4,5-Dihydro-1H-imidazol-2-yl)-4-propyl-3,4-dihydro-2H-benzo[1,4]oxazine::CHEMBL13940

SMILES: CCCN1CC(Oc2ccccc12)C1=NCCN1

InChI Key: InChIKey=PAQQKLNYFIWNPQ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50127596   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nischarin (Homo sapiens (Human))	BDBM50127596 (2-(4,5-Dihydro-1H-imidazol-2-yl)-4-propyl-3,4-dihy...) Show SMILES CCCN1CC(Oc2ccccc12)C1=NCCN1 |t:15| Show InChI InChI=1S/C14H19N3O/c1-2-9-17-10-13(14-15-7-8-16-14)18-12-6-4-3-5-11(12)17/h3-6,13H,2,7-10H2,1H3,(H,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Binding affinity for imidazoline receptor I-2 in rabbit kidney homogenate (relative to [3H]-Idazoxan radioligand)				J Med Chem 43: 1109-22 (2000) Article DOI: 10.1021/jm991124t BindingDB Entry DOI: 10.7270/Q2SB48G9
					More data for this Ligand-Target Pair
Imidazoline receptor 1 (I1R) (Homo sapiens (Human))	BDBM50127596 (2-(4,5-Dihydro-1H-imidazol-2-yl)-4-propyl-3,4-dihy...) Show SMILES CCCN1CC(Oc2ccccc12)C1=NCCN1 |t:15| Show InChI InChI=1S/C14H19N3O/c1-2-9-17-10-13(14-15-7-8-16-14)18-12-6-4-3-5-11(12)17/h3-6,13H,2,7-10H2,1H3,(H,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université d'Orléans Curated by ChEMBL					Assay Description In vitro binding affinity determined against imidazoline receptor I-2 using rabbit kidney preparation				J Med Chem 46: 1962-79 (2003) Article DOI: 10.1021/jm021050c BindingDB Entry DOI: 10.7270/Q22806Z1
					More data for this Ligand-Target Pair
Imidazoline receptor 1 (I1R) (Homo sapiens (Human))	BDBM50127596 (2-(4,5-Dihydro-1H-imidazol-2-yl)-4-propyl-3,4-dihy...) Show SMILES CCCN1CC(Oc2ccccc12)C1=NCCN1 |t:15| Show InChI InChI=1S/C14H19N3O/c1-2-9-17-10-13(14-15-7-8-16-14)18-12-6-4-3-5-11(12)17/h3-6,13H,2,7-10H2,1H3,(H,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Université d'Orléans Curated by ChEMBL					Assay Description In vitro binding affinity determined against imidazoline receptor I-2 using rabbit kidney preparation				J Med Chem 46: 1962-79 (2003) Article DOI: 10.1021/jm021050c BindingDB Entry DOI: 10.7270/Q22806Z1
					More data for this Ligand-Target Pair