BDBM50127619 5-Mercapto-pentanoic acid::CHEMBL294565
SMILES: OC(=O)CCCCS
InChI Key: InChIKey=GCIZMJUHGHGRNW-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate carboxypeptidase II (Homo sapiens (Human)) | BDBM50127619 (5-Mercapto-pentanoic acid | CHEMBL294565) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Eisai Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant GCP2 using N-acetyl-L-aspartyl-[3H]-L-glutamate as substrate by microplate assay | J Med Chem 55: 5922-32 (2012) Article DOI: 10.1021/jm300488m BindingDB Entry DOI: 10.7270/Q21J9BWN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate carboxypeptidase II (Homo sapiens (Human)) | BDBM50127619 (5-Mercapto-pentanoic acid | CHEMBL294565) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Guilford Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Inhibition of N-acetyl-L-aspartyl-[3H]-L-glutamate binding to glutamate carboxypeptidase II (GCP II) | J Med Chem 46: 1989-96 (2003) Article DOI: 10.1021/jm020515w BindingDB Entry DOI: 10.7270/Q2SQ8ZRG | |||||||||||
More data for this Ligand-Target Pair |