BDBM50127925 5-{3-Methyl-4-[3-(4-phenoxy-2-propyl-phenoxy)-propoxy]-phenyl}-thiazolidine-2,4-dione::CHEMBL54097

SMILES: CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc(cc1C)-c1sc(=O)[nH]c1O

InChI Key: InChIKey=CTZLMMJSKLKVAF-UHFFFAOYSA-N

Data: 3 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50127925   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50127925 (5-{3-Methyl-4-[3-(4-phenoxy-2-propyl-phenoxy)-prop...) Show SMILES CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc(cc1C)-c1sc(=O)[nH]c1O Show InChI InChI=1S/C28H29NO5S/c1-3-8-20-18-23(34-22-9-5-4-6-10-22)12-14-25(20)33-16-7-15-32-24-13-11-21(17-19(24)2)26-27(30)29-28(31)35-26/h4-6,9-14,17-18,30H,3,7-8,15-16H2,1-2H3,(H,29,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro agonist activity tested for transactivation in human PPAR delta-GAL4 chimeric COS-1 cells				Bioorg Med Chem Lett 13: 1801-4 (2003) BindingDB Entry DOI: 10.7270/Q2H994K2
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50127925 (5-{3-Methyl-4-[3-(4-phenoxy-2-propyl-phenoxy)-prop...) Show SMILES CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc(cc1C)-c1sc(=O)[nH]c1O Show InChI InChI=1S/C28H29NO5S/c1-3-8-20-18-23(34-22-9-5-4-6-10-22)12-14-25(20)33-16-7-15-32-24-13-11-21(17-19(24)2)26-27(30)29-28(31)35-26/h4-6,9-14,17-18,30H,3,7-8,15-16H2,1-2H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against human PPAR gamma (peroxisome proliferator-activated gamma receptor)				Bioorg Med Chem Lett 13: 1801-4 (2003) BindingDB Entry DOI: 10.7270/Q2H994K2
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50127925 (5-{3-Methyl-4-[3-(4-phenoxy-2-propyl-phenoxy)-prop...) Show SMILES CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc(cc1C)-c1sc(=O)[nH]c1O Show InChI InChI=1S/C28H29NO5S/c1-3-8-20-18-23(34-22-9-5-4-6-10-22)12-14-25(20)33-16-7-15-32-24-13-11-21(17-19(24)2)26-27(30)29-28(31)35-26/h4-6,9-14,17-18,30H,3,7-8,15-16H2,1-2H3,(H,29,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against human PPAR alpha (peroxisome proliferator-activated alpha receptor)				Bioorg Med Chem Lett 13: 1801-4 (2003) BindingDB Entry DOI: 10.7270/Q2H994K2
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50127925 (5-{3-Methyl-4-[3-(4-phenoxy-2-propyl-phenoxy)-prop...) Show SMILES CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc(cc1C)-c1sc(=O)[nH]c1O Show InChI InChI=1S/C28H29NO5S/c1-3-8-20-18-23(34-22-9-5-4-6-10-22)12-14-25(20)33-16-7-15-32-24-13-11-21(17-19(24)2)26-27(30)29-28(31)35-26/h4-6,9-14,17-18,30H,3,7-8,15-16H2,1-2H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
TBA					Assay Description Transactivation activity at Homo sapiens (human) PPARgamma				Citation and Details Article DOI: 10.1007/s00044-010-9428-9 BindingDB Entry DOI: 10.7270/Q22Z18FD
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50127925 (5-{3-Methyl-4-[3-(4-phenoxy-2-propyl-phenoxy)-prop...) Show SMILES CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc(cc1C)-c1sc(=O)[nH]c1O Show InChI InChI=1S/C28H29NO5S/c1-3-8-20-18-23(34-22-9-5-4-6-10-22)12-14-25(20)33-16-7-15-32-24-13-11-21(17-19(24)2)26-27(30)29-28(31)35-26/h4-6,9-14,17-18,30H,3,7-8,15-16H2,1-2H3,(H,29,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against human PPAR alpha (peroxisome proliferator-activated alpha receptor)				Bioorg Med Chem Lett 13: 1801-4 (2003) BindingDB Entry DOI: 10.7270/Q2H994K2
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50127925 (5-{3-Methyl-4-[3-(4-phenoxy-2-propyl-phenoxy)-prop...) Show SMILES CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc(cc1C)-c1sc(=O)[nH]c1O Show InChI InChI=1S/C28H29NO5S/c1-3-8-20-18-23(34-22-9-5-4-6-10-22)12-14-25(20)33-16-7-15-32-24-13-11-21(17-19(24)2)26-27(30)29-28(31)35-26/h4-6,9-14,17-18,30H,3,7-8,15-16H2,1-2H3,(H,29,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against human PPAR delta (peroxisome proliferator-activated delta receptor)				Bioorg Med Chem Lett 13: 1801-4 (2003) BindingDB Entry DOI: 10.7270/Q2H994K2
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50127925 (5-{3-Methyl-4-[3-(4-phenoxy-2-propyl-phenoxy)-prop...) Show SMILES CCCc1cc(Oc2ccccc2)ccc1OCCCOc1ccc(cc1C)-c1sc(=O)[nH]c1O Show InChI InChI=1S/C28H29NO5S/c1-3-8-20-18-23(34-22-9-5-4-6-10-22)12-14-25(20)33-16-7-15-32-24-13-11-21(17-19(24)2)26-27(30)29-28(31)35-26/h4-6,9-14,17-18,30H,3,7-8,15-16H2,1-2H3,(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro agonist activity tested for transactivation in human PPAR gamma-Gal4 chimeric COS-1 cells				Bioorg Med Chem Lett 13: 1801-4 (2003) BindingDB Entry DOI: 10.7270/Q2H994K2
					More data for this Ligand-Target Pair