BDBM50127949 3-(S)-Pyridin-3-yl-3-(2-{5-[2-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl)-ethyl]-thiophen-2-yl}-acetylamino)-propionic acid::CHEMBL53079
SMILES: OC(=O)C[C@H](NC(=O)Cc1ccc(CCc2ccc3CCCNc3n2)s1)c1cccnc1
InChI Key: InChIKey=WJPXEXNPOYDRHY-NRFANRHFSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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ITGAV/ITGB3 (Homo sapiens (Human)) | BDBM50127949 (3-(S)-Pyridin-3-yl-3-(2-{5-[2-(5,6,7,8-tetrahydro-...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 246 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Ability to bind to the alpha IIb beta3 integrin expressed as inhibitory concentration against ADP-stimulated aggregation of human gel-filtered platel... | Bioorg Med Chem Lett 13: 1809-12 (2003) BindingDB Entry DOI: 10.7270/Q2CJ8CVB | |||||||||||
More data for this Ligand-Target Pair |