BDBM50128122 CHEMBL3628107

SMILES: Clc1cc(NC(=O)c2cc3ccccc3o2)ccc1N1C(=O)c2ccccc2C1=O

InChI Key: InChIKey=IGNHQKFEFUUOHE-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50128122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50128122 (CHEMBL3628107) Show SMILES Clc1cc(NC(=O)c2cc3ccccc3o2)ccc1N1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C23H13ClN2O4/c24-17-12-14(25-21(27)20-11-13-5-1-4-8-19(13)30-20)9-10-18(17)26-22(28)15-6-2-3-7-16(15)23(26)29/h1-12H,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ...				J Med Chem 58: 7959-71 (2015) BindingDB Entry DOI: 10.7270/Q2MK6FQ4
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50128122 (CHEMBL3628107) Show SMILES Clc1cc(NC(=O)c2cc3ccccc3o2)ccc1N1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C23H13ClN2O4/c24-17-12-14(25-21(27)20-11-13-5-1-4-8-19(13)30-20)9-10-18(17)26-22(28)15-6-2-3-7-16(15)23(26)29/h1-12H,(H,25,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu1 receptor in HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliztion by Fluo-4AM ...				J Med Chem 58: 7959-71 (2015) BindingDB Entry DOI: 10.7270/Q2MK6FQ4
					More data for this Ligand-Target Pair