BDBM50128491 ((2R,4S)-2,6-Dimethyl-4-p-tolylamino-3,4-dihydro-2H-quinolin-1-yl)-(2-trifluoromethyl-phenyl)-methanone::CHEMBL58140

SMILES: C[C@@H]1C[C@H](Nc2ccc(C)cc2)c2cc(C)ccc2N1C(=O)c1ccccc1C(F)(F)F

InChI Key: InChIKey=CVBHDWJVOPGPSJ-JPYJTQIMSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50128491   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ecdysone receptor (Aedes aegypti)	BDBM50128491 (((2R,4S)-2,6-Dimethyl-4-p-tolylamino-3,4-dihydro-2...) Show SMILES C[C@@H]1C[C@H](Nc2ccc(C)cc2)c2cc(C)ccc2N1C(=O)c1ccccc1C(F)(F)F Show InChI InChI=1S/C26H25F3N2O/c1-16-8-11-19(12-9-16)30-23-15-18(3)31(24-13-10-17(2)14-21(23)24)25(32)20-6-4-5-7-22(20)26(27,28)29/h4-14,18,23,30H,15H2,1-3H3/t18-,23+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	3.33E+4	n/a	n/a	n/a	n/a
RHeoGene Curated by ChEMBL					Assay Description Effective concentration for ecdysone-dependent transactivation in mammalian cell line expressing Aedes aegypti ecdysone receptor				Bioorg Med Chem Lett 13: 1943-6 (2003) BindingDB Entry DOI: 10.7270/Q2NV9HN8
					More data for this Ligand-Target Pair