BDBM50128573 CHEMBL77250::Cyclohexyl-carbamic acid naphthalen-2-yl ester::US8815951, 110::naphthalen-2-yl cyclohexylcarbamate

SMILES: O=C(NC1CCCCC1)Oc1ccc2ccccc2c1

InChI Key: InChIKey=ZYHUWMGJJOBBCF-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50128573   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epoxide hydrolase (MsEH) (Mus musculus (Mouse))	BDBM50128573 (CHEMBL77250 | Cyclohexyl-carbamic acid naphthalen-...) Show SMILES O=C(NC1CCCCC1)Oc1ccc2ccccc2c1 Show InChI InChI=1S/C17H19NO2/c19-17(18-15-8-2-1-3-9-15)20-16-11-10-13-6-4-5-7-14(13)12-16/h4-7,10-12,15H,1-3,8-9H2,(H,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description The invention also provide methods for assaying for epoxide hydrolase activity as diagnostic assay to identify individuals at increased risk for hype...				US Patent US8815951 (2014) BindingDB Entry DOI: 10.7270/Q2BP01G9
					More data for this Ligand-Target Pair
Epoxide hydrolase 1 (Homo sapiens (Human))	BDBM50128573 (CHEMBL77250 | Cyclohexyl-carbamic acid naphthalen-...) Show SMILES O=C(NC1CCCCC1)Oc1ccc2ccccc2c1 Show InChI InChI=1S/C17H19NO2/c19-17(18-15-8-2-1-3-9-15)20-16-11-10-13-6-4-5-7-14(13)12-16/h4-7,10-12,15H,1-3,8-9H2,(H,18,19)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
The Regents of the University of California US Patent					Assay Description The invention also provide methods for assaying for epoxide hydrolase activity as diagnostic assay to identify individuals at increased risk for hype...				US Patent US8815951 (2014) BindingDB Entry DOI: 10.7270/Q2BP01G9
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50128573 (CHEMBL77250 | Cyclohexyl-carbamic acid naphthalen-...) Show SMILES O=C(NC1CCCCC1)Oc1ccc2ccccc2c1 Show InChI InChI=1S/C17H19NO2/c19-17(18-15-8-2-1-3-9-15)20-16-11-10-13-6-4-5-7-14(13)12-16/h4-7,10-12,15H,1-3,8-9H2,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	324	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human FAAH				J Med Chem 51: 7327-43 (2009) Article DOI: 10.1021/jm800311k BindingDB Entry DOI: 10.7270/Q2J67HT8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50128573 (CHEMBL77250 | Cyclohexyl-carbamic acid naphthalen-...) Show SMILES O=C(NC1CCCCC1)Oc1ccc2ccccc2c1 Show InChI InChI=1S/C17H19NO2/c19-17(18-15-8-2-1-3-9-15)20-16-11-10-13-6-4-5-7-14(13)12-16/h4-7,10-12,15H,1-3,8-9H2,(H,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of FAAH				Bioorg Med Chem Lett 21: 4674-85 (2011) Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50128573 (CHEMBL77250 | Cyclohexyl-carbamic acid naphthalen-...) Show SMILES O=C(NC1CCCCC1)Oc1ccc2ccccc2c1 Show InChI InChI=1S/C17H19NO2/c19-17(18-15-8-2-1-3-9-15)20-16-11-10-13-6-4-5-7-14(13)12-16/h4-7,10-12,15H,1-3,8-9H2,(H,18,19)	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	324	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Urbino Carlo Bo Curated by ChEMBL					Assay Description Inhibition of [3H]anandamide binding to fatty acid amide hydrolase of rat brain membrane				J Med Chem 46: 2352-60 (2003) Article DOI: 10.1021/jm021119g BindingDB Entry DOI: 10.7270/Q2DB817C
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50128573 (CHEMBL77250 | Cyclohexyl-carbamic acid naphthalen-...) Show SMILES O=C(NC1CCCCC1)Oc1ccc2ccccc2c1 Show InChI InChI=1S/C17H19NO2/c19-17(18-15-8-2-1-3-9-15)20-16-11-10-13-6-4-5-7-14(13)12-16/h4-7,10-12,15H,1-3,8-9H2,(H,18,19)	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	324	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Urbino Carlo Bo Curated by ChEMBL					Assay Description Fatty acid amide hydrolase inhibitory activity in rat brain membrane using [3H]-anandamide as a substrate				J Med Chem 46: 2352-60 (2003) Article DOI: 10.1021/jm021119g BindingDB Entry DOI: 10.7270/Q2DB817C
					More data for this Ligand-Target Pair