BDBM50129091 CHEMBL62496::N-Methyl-N-{2-[2-(3-methyl-4-oxazol-5-yl-phenylamino)-oxazol-5-yl]-phenyl}-2-morpholin-4-yl-acetamide

SMILES: CN(C(=O)CN1CCOCC1)c1ccccc1-c1cnc(Nc2ccc(-c3cnco3)c(C)c2)o1

InChI Key: InChIKey=CGKIMAMLPGQXAA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129091   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human))	BDBM50129091 (CHEMBL62496 | N-Methyl-N-{2-[2-(3-methyl-4-oxazol-...) Show SMILES CN(C(=O)CN1CCOCC1)c1ccccc1-c1cnc(Nc2ccc(-c3cnco3)c(C)c2)o1 Show InChI InChI=1S/C26H27N5O4/c1-18-13-19(7-8-20(18)23-14-27-17-34-23)29-26-28-15-24(35-26)21-5-3-4-6-22(21)30(2)25(32)16-31-9-11-33-12-10-31/h3-8,13-15,17H,9-12,16H2,1-2H3,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of inosine-5'-monophosphate dehydrogenase 2.				Bioorg Med Chem Lett 13: 2059-63 (2003) BindingDB Entry DOI: 10.7270/Q22Z14X1
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