BDBM50129101 1-(4-Oxazol-5-yl-phenyl)-3-m-tolyl-urea::CHEMBL62232
SMILES: Cc1cccc(NC(=O)Nc2ccc(cc2)-c2cnco2)c1
InChI Key: InChIKey=AISMDELMNHIKBP-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2) (Homo sapiens (Human)) | BDBM50129101 (1-(4-Oxazol-5-yl-phenyl)-3-m-tolyl-urea | CHEMBL62...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of inosine-5'-monophosphate dehydrogenase 2. | Bioorg Med Chem Lett 13: 2059-63 (2003) BindingDB Entry DOI: 10.7270/Q22Z14X1 | |||||||||||
More data for this Ligand-Target Pair |