BDBM50129169 9-Bromo-7-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::9-bromo-7-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline::CHEMBL294265

SMILES: COc1cc(Br)cc-2c1OCc1c-2ccc2NC(C)(C)C=C(C)c12

InChI Key: InChIKey=MZIFJAQJEZFKDE-UHFFFAOYSA-N

Data: 2 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50129169   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50129169 (9-Bromo-7-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6...) Show SMILES COc1cc(Br)cc-2c1OCc1c-2ccc2NC(C)(C)C=C(C)c12 |t:22| Show InChI InChI=1S/C20H20BrNO2/c1-11-9-20(2,3)22-16-6-5-13-14-7-12(21)8-17(23-4)19(14)24-10-15(13)18(11)16/h5-9,22H,10H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	476	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity at human progesterone receptor.				Bioorg Med Chem Lett 13: 2075-8 (2003) BindingDB Entry DOI: 10.7270/Q2P55P2M
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50129169 (9-Bromo-7-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6...) Show SMILES COc1cc(Br)cc-2c1OCc1c-2ccc2NC(C)(C)C=C(C)c12 |t:22| Show InChI InChI=1S/C20H20BrNO2/c1-11-9-20(2,3)22-16-6-5-13-14-7-12(21)8-17(23-4)19(14)24-10-15(13)18(11)16/h5-9,22H,10H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	479	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scientific Computing Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]progesterone from Progesterone receptor				J Med Chem 49: 4261-8 (2006) Article DOI: 10.1021/jm060234e BindingDB Entry DOI: 10.7270/Q2V69NB6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50129169 (9-Bromo-7-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6...) Show SMILES COc1cc(Br)cc-2c1OCc1c-2ccc2NC(C)(C)C=C(C)c12 |t:22| Show InChI InChI=1S/C20H20BrNO2/c1-11-9-20(2,3)22-16-6-5-13-14-7-12(21)8-17(23-4)19(14)24-10-15(13)18(11)16/h5-9,22H,10H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonistic activity at human progesterone receptor in CV-1 cells.				Bioorg Med Chem Lett 13: 2075-8 (2003) BindingDB Entry DOI: 10.7270/Q2P55P2M
					More data for this Ligand-Target Pair