BDBM50129662 3-(2-Methoxy-phenyl)-acrylic acid 2-(thiazol-2-ylcarbamoyl)-pyridin-3-yl ester::CHEMBL89269

SMILES: COc1ccccc1\C=C\C(=O)Oc1cccnc1C(=O)Nc1nccs1

InChI Key: InChIKey=VMLGKIFAJHYRQG-CMDGGOBGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50129662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50129662 (3-(2-Methoxy-phenyl)-acrylic acid 2-(thiazol-2-ylc...) Show SMILES COc1ccccc1\C=C\C(=O)Oc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C19H15N3O4S/c1-25-14-6-3-2-5-13(14)8-9-16(23)26-15-7-4-10-20-17(15)18(24)22-19-21-11-12-27-19/h2-12H,1H3,(H,21,22,24)/b9-8+	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli				J Med Chem 46: 2631-40 (2003) Article DOI: 10.1021/jm0300532 BindingDB Entry DOI: 10.7270/Q2CF9QTC
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50129662 (3-(2-Methoxy-phenyl)-acrylic acid 2-(thiazol-2-ylc...) Show SMILES COc1ccccc1\C=C\C(=O)Oc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C19H15N3O4S/c1-25-14-6-3-2-5-13(14)8-9-16(23)26-15-7-4-10-20-17(15)18(24)22-19-21-11-12-27-19/h2-12H,1H3,(H,21,22,24)/b9-8+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae				J Med Chem 46: 2631-40 (2003) Article DOI: 10.1021/jm0300532 BindingDB Entry DOI: 10.7270/Q2CF9QTC
					More data for this Ligand-Target Pair