BDBM50129668 3-Bromo-4-fluoro-benzoic acid 2-(thiazol-2-ylcarbamoyl)-pyridin-3-yl ester::CHEMBL328363

SMILES: Fc1ccc(cc1Br)C(=O)Oc1cccnc1C(=O)Nc1nccs1

InChI Key: InChIKey=ITABIKMNLCVNIZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50129668   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine Aminopeptidase (MAP) (Escherichia coli (strain K12))	BDBM50129668 (3-Bromo-4-fluoro-benzoic acid 2-(thiazol-2-ylcarba...) Show SMILES Fc1ccc(cc1Br)C(=O)Oc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C16H9BrFN3O3S/c17-10-8-9(3-4-11(10)18)15(23)24-12-2-1-5-19-13(12)14(22)21-16-20-6-7-25-16/h1-8H,(H,20,21,22)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against Methionine aminopeptidase 1 from Escherichia coli				J Med Chem 46: 2631-40 (2003) Article DOI: 10.1021/jm0300532 BindingDB Entry DOI: 10.7270/Q2CF9QTC
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM50129668 (3-Bromo-4-fluoro-benzoic acid 2-(thiazol-2-ylcarba...) Show SMILES Fc1ccc(cc1Br)C(=O)Oc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C16H9BrFN3O3S/c17-10-8-9(3-4-11(10)18)15(23)24-12-2-1-5-19-13(12)14(22)21-16-20-6-7-25-16/h1-8H,(H,20,21,22)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against type I methionine aminopeptidase from Saccharomyces cerevisiae				J Med Chem 46: 2631-40 (2003) Article DOI: 10.1021/jm0300532 BindingDB Entry DOI: 10.7270/Q2CF9QTC
					More data for this Ligand-Target Pair