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SMILES: OC(=O)[C@H](Cc1ccccc1)N1C(=O)N[C@@H](Cc2ccc(cc2)-c2ccc(Cl)cc2)C1=O

InChI Key: InChIKey=SQUYQSJFXLRDCP-VXKWHMMOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130046   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM50130046
PNG
(CHEMBL3629647)
Show SMILES OC(=O)[C@H](Cc1ccccc1)N1C(=O)N[C@@H](Cc2ccc(cc2)-c2ccc(Cl)cc2)C1=O |r|
Show InChI InChI=1S/C25H21ClN2O4/c26-20-12-10-19(11-13-20)18-8-6-17(7-9-18)14-21-23(29)28(25(32)27-21)22(24(30)31)15-16-4-2-1-3-5-16/h1-13,21-22H,14-15H2,(H,27,32)(H,30,31)/t21-,22-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
>5.00E+4n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Competitive binding affinity to Bcl-2 (unknown origin) preincubated for 30 mins followed by 5-FAM-Bid-BH3 peptide addition measured after 20 mins by ...

Bioorg Med Chem 23: 7359-65 (2015)


BindingDB Entry DOI: 10.7270/Q2FQ9ZD8
More data for this
Ligand-Target Pair