BDBM50130193 CHEMBL3628510

SMILES: OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N1C(=O)N[C@@H](Cc2ccc(cc2)-c2ccc(Cl)cc2)C1=O

InChI Key: InChIKey=SJXPICRXPXGKCI-DTXPUJKBSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130193   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50130193 (CHEMBL3628510) Show SMILES OC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N1C(=O)N[C@@H](Cc2ccc(cc2)-c2ccc(Cl)cc2)C1=O |r| Show InChI InChI=1S/C34H30ClN3O5/c35-27-17-15-26(16-18-27)25-13-11-24(12-14-25)19-28-32(40)38(34(43)37-28)30(21-23-9-5-2-6-10-23)31(39)36-29(33(41)42)20-22-7-3-1-4-8-22/h1-18,28-30H,19-21H2,(H,36,39)(H,37,43)(H,41,42)/t28-,29-,30-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Competitive binding affinity to Bcl-2 (unknown origin) preincubated for 30 mins followed by 5-FAM-Bid-BH3 peptide addition measured after 20 mins by ...				Bioorg Med Chem 23: 7359-65 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9ZD8
					More data for this Ligand-Target Pair