BDBM50130219 CHEMBL81809::Morpholine-4-carboxylic acid 6,8-dichloro-9H-beta-carbolin-7-yl ester

SMILES: Clc1cc2c3cc[nH]cc3nc2c(Cl)c1OC(=O)N1CCOCC1

InChI Key: InChIKey=DHKMNEGHKGCLOW-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50130219   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit alpha (Homo sapiens (Human))	BDBM50130219 (CHEMBL81809 | Morpholine-4-carboxylic acid 6,8-dic...) Show SMILES Clc1cc2c3cc[nH]cc3nc2c(Cl)c1OC(=O)N1CCOCC1 Show InChI InChI=1S/C16H13Cl2N3O3/c17-11-7-10-9-1-2-19-8-12(9)20-14(10)13(18)15(11)24-16(22)21-3-5-23-6-4-21/h1-2,7-8,19H,3-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against IkappaB kinase(IKK) isolated from HeLa cells activated with recombinant MEEK1 in an ELISA phosphorylaton assay.				Bioorg Med Chem Lett 13: 2419-22 (2003) BindingDB Entry DOI: 10.7270/Q2PK0FJ7
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase (PKA) (Homo sapiens (Human))	BDBM50130219 (CHEMBL81809 | Morpholine-4-carboxylic acid 6,8-dic...) Show SMILES Clc1cc2c3cc[nH]cc3nc2c(Cl)c1OC(=O)N1CCOCC1 Show InChI InChI=1S/C16H13Cl2N3O3/c17-11-7-10-9-1-2-19-8-12(9)20-14(10)13(18)15(11)24-16(22)21-3-5-23-6-4-21/h1-2,7-8,19H,3-6H2	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against protein kinase A.				Bioorg Med Chem Lett 13: 2419-22 (2003) BindingDB Entry DOI: 10.7270/Q2PK0FJ7
					More data for this Ligand-Target Pair
Protein kinase C (PKC) (Homo sapiens (Human))	BDBM50130219 (CHEMBL81809 | Morpholine-4-carboxylic acid 6,8-dic...) Show SMILES Clc1cc2c3cc[nH]cc3nc2c(Cl)c1OC(=O)N1CCOCC1 Show InChI InChI=1S/C16H13Cl2N3O3/c17-11-7-10-9-1-2-19-8-12(9)20-14(10)13(18)15(11)24-16(22)21-3-5-23-6-4-21/h1-2,7-8,19H,3-6H2	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibitory activity against protein kinase C.				Bioorg Med Chem Lett 13: 2419-22 (2003) BindingDB Entry DOI: 10.7270/Q2PK0FJ7
					More data for this Ligand-Target Pair