BDBM50130435 3-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl]-benzamide::CHEMBL103550

SMILES: CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3cccc(F)c3)nc12

InChI Key: InChIKey=ZOQSROUPADLHKR-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50130435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50130435 (3-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...) Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3cccc(F)c3)nc12 Show InChI InChI=1S/C20H21FN4O/c1-25-9-7-13(8-10-25)16-12-22-17-5-6-18(23-19(16)17)24-20(26)14-3-2-4-15(21)11-14/h2-6,11-13,22H,7-10H2,1H3,(H,23,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor				J Med Chem 46: 3060-71 (2003) Article DOI: 10.1021/jm030020m BindingDB Entry DOI: 10.7270/Q21V5DCB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50130435 (3-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...) Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3cccc(F)c3)nc12 Show InChI InChI=1S/C20H21FN4O/c1-25-9-7-13(8-10-25)16-12-22-17-5-6-18(23-19(16)17)24-20(26)14-3-2-4-15(21)11-14/h2-6,11-13,22H,7-10H2,1H3,(H,23,24,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	135	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1A recepto...				J Med Chem 46: 3060-71 (2003) Article DOI: 10.1021/jm030020m BindingDB Entry DOI: 10.7270/Q21V5DCB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50130435 (3-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...) Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3cccc(F)c3)nc12 Show InChI InChI=1S/C20H21FN4O/c1-25-9-7-13(8-10-25)16-12-22-17-5-6-18(23-19(16)17)24-20(26)14-3-2-4-15(21)11-14/h2-6,11-13,22H,7-10H2,1H3,(H,23,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1D recepto...				J Med Chem 46: 3060-71 (2003) Article DOI: 10.1021/jm030020m BindingDB Entry DOI: 10.7270/Q21V5DCB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50130435 (3-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-pyrrolo...) Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3cccc(F)c3)nc12 Show InChI InChI=1S/C20H21FN4O/c1-25-9-7-13(8-10-25)16-12-22-17-5-6-18(23-19(16)17)24-20(26)14-3-2-4-15(21)11-14/h2-6,11-13,22H,7-10H2,1H3,(H,23,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1B recepto...				J Med Chem 46: 3060-71 (2003) Article DOI: 10.1021/jm030020m BindingDB Entry DOI: 10.7270/Q21V5DCB
					More data for this Ligand-Target Pair