BDBM50130474 4-Fluoro-N-[3-(1-propyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl]-benzamide::CHEMBL105478

SMILES: CCCN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(F)cc3)nc12

InChI Key: InChIKey=AGNQRCZHJFDENL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50130474 (4-Fluoro-N-[3-(1-propyl-piperidin-4-yl)-1H-pyrrolo...) Show SMILES CCCN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccc(F)cc3)nc12 Show InChI InChI=1S/C22H25FN4O/c1-2-11-27-12-9-15(10-13-27)18-14-24-19-7-8-20(25-21(18)19)26-22(28)16-3-5-17(23)6-4-16/h3-8,14-15,24H,2,9-13H2,1H3,(H,25,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor				J Med Chem 46: 3060-71 (2003) Article DOI: 10.1021/jm030020m BindingDB Entry DOI: 10.7270/Q21V5DCB
					More data for this Ligand-Target Pair