BDBM50130566 CHEMBL542692::N-(6-Oxo-5,6-dihydro-benzo[c][1,5]naphthyridin-3-yl)-2-(4-pyrrolidin-1-yl-piperidin-1-yl)-acetamide; hydrochloride

SMILES: O=C(CN1CCC(CC1)N1CCCC1)Nc1cnc2c(c1)[nH]c(=O)c1ccccc21

InChI Key: InChIKey=CMQRPACWOBBRED-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50130566 (CHEMBL542692 | N-(6-Oxo-5,6-dihydro-benzo[c][1,5]n...) Show SMILES O=C(CN1CCC(CC1)N1CCCC1)Nc1cnc2c(c1)[nH]c(=O)c1ccccc21 Show InChI InChI=1S/C23H27N5O2/c29-21(15-27-11-7-17(8-12-27)28-9-3-4-10-28)25-16-13-20-22(24-14-16)18-5-1-2-6-19(18)23(30)26-20/h1-2,5-6,13-14,17H,3-4,7-12,15H2,(H,25,29)(H,26,30)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	134	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc Curated by ChEMBL					Assay Description Inhibitory activity against Poly (ADP-ribose) polymerase 1				J Med Chem 46: 3138-51 (2003) Article DOI: 10.1021/jm030109s BindingDB Entry DOI: 10.7270/Q2Z89D5P
					More data for this Ligand-Target Pair