BDBM50130764 CHEMBL3634859

SMILES: Cn1ccc2nc(COc3ccc(cc3)-c3ccc(=O)[nH]c3-c3ccncc3)ccc12

InChI Key: InChIKey=KSBYZIGNXVSCPR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130764   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50130764 (CHEMBL3634859) Show SMILES Cn1ccc2nc(COc3ccc(cc3)-c3ccc(=O)[nH]c3-c3ccncc3)ccc12 Show InChI InChI=1S/C25H20N4O2/c1-29-15-12-22-23(29)8-4-19(27-22)16-31-20-5-2-17(3-6-20)21-7-9-24(30)28-25(21)18-10-13-26-14-11-18/h2-15H,16H2,1H3,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Research Centre Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...				J Med Chem 58: 8292-308 (2015) BindingDB Entry DOI: 10.7270/Q2833TVD
					More data for this Ligand-Target Pair