BDBM50130861 CHEMBL3634849

SMILES: O=c1ccc(-c2ccc(OCc3ccc4ncccc4n3)cc2)c([nH]1)-c1ccccc1

InChI Key: InChIKey=JVPIKNZSDPNTBW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130861   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50130861 (CHEMBL3634849) Show SMILES O=c1ccc(-c2ccc(OCc3ccc4ncccc4n3)cc2)c([nH]1)-c1ccccc1 Show InChI InChI=1S/C26H19N3O2/c30-25-15-13-22(26(29-25)19-5-2-1-3-6-19)18-8-11-21(12-9-18)31-17-20-10-14-23-24(28-20)7-4-16-27-23/h1-16H,17H2,(H,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Research Centre Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...				J Med Chem 58: 8292-308 (2015) BindingDB Entry DOI: 10.7270/Q2833TVD
					More data for this Ligand-Target Pair