BDBM50130864 CHEMBL3634852

SMILES: Fc1ccc(cc1)-c1[nH]c(=O)ccc1-c1ccc(OCc2nc3ccccc3s2)cc1

InChI Key: InChIKey=IKQVLJOTHQPZJL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130864   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50130864 (CHEMBL3634852) Show SMILES Fc1ccc(cc1)-c1[nH]c(=O)ccc1-c1ccc(OCc2nc3ccccc3s2)cc1 Show InChI InChI=1S/C25H17FN2O2S/c26-18-9-5-17(6-10-18)25-20(13-14-23(29)28-25)16-7-11-19(12-8-16)30-15-24-27-21-3-1-2-4-22(21)31-24/h1-14H,15H2,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	926	n/a	n/a	n/a	n/a	n/a	n/a
Glenmark Research Centre Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human PDE10A using [3H]cAMP/cAMP as substrate assessed as hydrolysis of [3H]cAMP to [3H]AMP after 30 ...				J Med Chem 58: 8292-308 (2015) BindingDB Entry DOI: 10.7270/Q2833TVD
					More data for this Ligand-Target Pair