BDBM50131111 CHEMBL87258::H-SMGLPCVVM-OH
SMILES: CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CCSC)NC(=O)[C@@H](N)CO)C(C)C)C(C)C)C(O)=O
InChI Key: InChIKey=XSTRKZMDUHFCKT-LFPOIMSVSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Protein Farnesyltransferase (PFT) (Bos taurus (bovine)) | BDBM50131111 (CHEMBL87258 | H-SMGLPCVVM-OH) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL | Assay Description In vitro inhibition of farnesylation of v-Ki-Ras by bovine farnesyl transferase | Bioorg Med Chem Lett 13: 2583-6 (2003) BindingDB Entry DOI: 10.7270/Q2KK9B5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein Farnesyltransferase (PFT) (Homo sapiens (Human)) | BDBM50131111 (CHEMBL87258 | H-SMGLPCVVM-OH) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL | Assay Description Inhibition of Farnesyltransferase by Scintillation Proximity Assay | Bioorg Med Chem Lett 13: 2583-6 (2003) BindingDB Entry DOI: 10.7270/Q2KK9B5J | |||||||||||
More data for this Ligand-Target Pair |