BDBM50131526 (R)-2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxy-2-(4-(2-(methylamino)ethoxy)phenyl)acetamide::(R)-2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-2-[4-(2-methylamino-ethoxy)-phenyl]-acetamide::CHEMBL98061

SMILES: CNCCOc1ccc(cc1)[C@@H](N(C)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO

InChI Key: InChIKey=QCHHXEMLMRDLDA-OAQYLSRUSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50131526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131526 ((R)-2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido...) Show SMILES CNCCOc1ccc(cc1)[C@@H](N(C)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO Show InChI InChI=1S/C22H27N3O6S/c1-4-5-15-30-19-10-12-20(13-11-19)32(28,29)25(3)21(22(26)24-27)17-6-8-18(9-7-17)31-16-14-23-2/h6-13,21,23,27H,14-16H2,1-3H3,(H,24,26)/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibition of Matrix metalloprotein-9				Bioorg Med Chem Lett 13: 2799-803 (2003) BindingDB Entry DOI: 10.7270/Q21N80H7
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50131526 ((R)-2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido...) Show SMILES CNCCOc1ccc(cc1)[C@@H](N(C)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO Show InChI InChI=1S/C22H27N3O6S/c1-4-5-15-30-19-10-12-20(13-11-19)32(28,29)25(3)21(22(26)24-27)17-6-8-18(9-7-17)31-16-14-23-2/h6-13,21,23,27H,14-16H2,1-3H3,(H,24,26)/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	927	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibition of Matrix metalloprotein 1				Bioorg Med Chem Lett 13: 2799-803 (2003) BindingDB Entry DOI: 10.7270/Q21N80H7
					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131526 ((R)-2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido...) Show SMILES CNCCOc1ccc(cc1)[C@@H](N(C)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO Show InChI InChI=1S/C22H27N3O6S/c1-4-5-15-30-19-10-12-20(13-11-19)32(28,29)25(3)21(22(26)24-27)17-6-8-18(9-7-17)31-16-14-23-2/h6-13,21,23,27H,14-16H2,1-3H3,(H,24,26)/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP9				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50131526 ((R)-2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido...) Show SMILES CNCCOc1ccc(cc1)[C@@H](N(C)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO Show InChI InChI=1S/C22H27N3O6S/c1-4-5-15-30-19-10-12-20(13-11-19)32(28,29)25(3)21(22(26)24-27)17-6-8-18(9-7-17)31-16-14-23-2/h6-13,21,23,27H,14-16H2,1-3H3,(H,24,26)/t21-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibition of Matrix metalloprotein 13				Bioorg Med Chem Lett 13: 2799-803 (2003) BindingDB Entry DOI: 10.7270/Q21N80H7
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50131526 ((R)-2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido...) Show SMILES CNCCOc1ccc(cc1)[C@@H](N(C)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO Show InChI InChI=1S/C22H27N3O6S/c1-4-5-15-30-19-10-12-20(13-11-19)32(28,29)25(3)21(22(26)24-27)17-6-8-18(9-7-17)31-16-14-23-2/h6-13,21,23,27H,14-16H2,1-3H3,(H,24,26)/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	933	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP1				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50131526 ((R)-2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido...) Show SMILES CNCCOc1ccc(cc1)[C@@H](N(C)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO Show InChI InChI=1S/C22H27N3O6S/c1-4-5-15-30-19-10-12-20(13-11-19)32(28,29)25(3)21(22(26)24-27)17-6-8-18(9-7-17)31-16-14-23-2/h6-13,21,23,27H,14-16H2,1-3H3,(H,24,26)/t21-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibition of tumor necrosis factor-alpha converting enzyme				Bioorg Med Chem Lett 13: 2799-803 (2003) BindingDB Entry DOI: 10.7270/Q21N80H7
					More data for this Ligand-Target Pair