BDBM50131535 CHEMBL94386::N-Hydroxy-2-[methyl-(4-prop-2-ynylamino-benzenesulfonyl)-amino]-acetamide

SMILES: CN(CC(=O)NO)S(=O)(=O)c1ccc(NCC#C)cc1

InChI Key: InChIKey=DFRHCKHXGKQVLI-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131535   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50131535 (CHEMBL94386 | N-Hydroxy-2-[methyl-(4-prop-2-ynylam...) Show SMILES CN(CC(=O)NO)S(=O)(=O)c1ccc(NCC#C)cc1 Show InChI InChI=1S/C12H15N3O4S/c1-3-8-13-10-4-6-11(7-5-10)20(18,19)15(2)9-12(16)14-17/h1,4-7,13,17H,8-9H2,2H3,(H,14,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibition of Matrix metalloprotein-9				Bioorg Med Chem Lett 13: 2799-803 (2003) BindingDB Entry DOI: 10.7270/Q21N80H7
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50131535 (CHEMBL94386 | N-Hydroxy-2-[methyl-(4-prop-2-ynylam...) Show SMILES CN(CC(=O)NO)S(=O)(=O)c1ccc(NCC#C)cc1 Show InChI InChI=1S/C12H15N3O4S/c1-3-8-13-10-4-6-11(7-5-10)20(18,19)15(2)9-12(16)14-17/h1,4-7,13,17H,8-9H2,2H3,(H,14,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	751	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibition of Matrix metalloprotein 13				Bioorg Med Chem Lett 13: 2799-803 (2003) BindingDB Entry DOI: 10.7270/Q21N80H7
					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50131535 (CHEMBL94386 | N-Hydroxy-2-[methyl-(4-prop-2-ynylam...) Show SMILES CN(CC(=O)NO)S(=O)(=O)c1ccc(NCC#C)cc1 Show InChI InChI=1S/C12H15N3O4S/c1-3-8-13-10-4-6-11(7-5-10)20(18,19)15(2)9-12(16)14-17/h1,4-7,13,17H,8-9H2,2H3,(H,14,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description In vitro inhibition of tumor necrosis factor-alpha converting enzyme				Bioorg Med Chem Lett 13: 2799-803 (2003) BindingDB Entry DOI: 10.7270/Q21N80H7
					More data for this Ligand-Target Pair