BDBM50132336 CHEMBL407129
SMILES: CC(C)C[C@H](NC(=O)Cc1ccccc1)C(=O)N[C@@H](CC1CCCCC1)C(=O)N(C)C
InChI Key: InChIKey=WBRNNKFGYQBZRG-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Presenilin-1 (Homo sapiens (Human)) | BDBM50132336 (CHEMBL407129) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 102 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of gamma-secretase activity in H4 human neuroglioma cells by measuring amyloid beta production | Bioorg Med Chem Lett 14: 1917-21 (2004) BindingDB Entry DOI: 10.7270/Q2TT4T4K | |||||||||||
More data for this Ligand-Target Pair |