null

SMILES: COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCCC(=O)NO

InChI Key: InChIKey=AAFHYERZITZNLX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132346   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50132346 (CHEMBL3633762) Show SMILES COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCCC(=O)NO Show InChI InChI=1S/C18H17BrN4O4/c1-26-15-9-14-13(8-16(15)27-6-5-17(24)23-25)18(21-10-20-14)22-12-4-2-3-11(19)7-12/h2-4,7-10,25H,5-6H2,1H3,(H,23,24)(H,20,21,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	531	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibitory concentration against C-C chemokine receptor type 3				Bioorg Med Chem Lett 25: 5137-41 (2015) BindingDB Entry DOI: 10.7270/Q2CN75QQ
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50132346 (CHEMBL3633762) Show SMILES COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCCC(=O)NO Show InChI InChI=1S/C18H17BrN4O4/c1-26-15-9-14-13(8-16(15)27-6-5-17(24)23-25)18(21-10-20-14)22-12-4-2-3-11(19)7-12/h2-4,7-10,25H,5-6H2,1H3,(H,23,24)(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	625	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Binding affinity for prostanoid EP4 receptor				Bioorg Med Chem Lett 25: 5137-41 (2015) BindingDB Entry DOI: 10.7270/Q2CN75QQ
					More data for this Ligand-Target Pair