BDBM50132777 CHEMBL3634427

SMILES: Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(c1)C(F)(F)F

InChI Key: InChIKey=CVOJZCARFHUPQD-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132777   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50132777 (CHEMBL3634427) Show SMILES Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(c1)C(F)(F)F Show InChI InChI=1S/C22H15F3N2O4/c1-11-4-3-5-14-17(11)21(30)27(20(14)29)16-7-6-13(10-15(16)22(23,24)25)26-19(28)18-12(2)8-9-31-18/h3-10H,1-2H3,(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	530	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Agonist activity at human NPY4 receptor in HEK293 cells by inhibition of forskolin-stimulated cAMP synthesis				Bioorg Med Chem Lett 25: 5107-10 (2015) BindingDB Entry DOI: 10.7270/Q20C4XKQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Homo sapiens (Human))	BDBM50132777 (CHEMBL3634427) Show SMILES Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(c1)C(F)(F)F Show InChI InChI=1S/C22H15F3N2O4/c1-11-4-3-5-14-17(11)21(30)27(20(14)29)16-7-6-13(10-15(16)22(23,24)25)26-19(28)18-12(2)8-9-31-18/h3-10H,1-2H3,(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	5.76E+3	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay				Bioorg Med Chem Lett 25: 5107-10 (2015) BindingDB Entry DOI: 10.7270/Q20C4XKQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50132777 (CHEMBL3634427) Show SMILES Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)c(c1)C(F)(F)F Show InChI InChI=1S/C22H15F3N2O4/c1-11-4-3-5-14-17(11)21(30)27(20(14)29)16-7-6-13(10-15(16)22(23,24)25)26-19(28)18-12(2)8-9-31-18/h3-10H,1-2H3,(H,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	537	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR1 by calcium mobilization assay				Bioorg Med Chem Lett 25: 5107-10 (2015) BindingDB Entry DOI: 10.7270/Q20C4XKQ
					More data for this Ligand-Target Pair